2024
Odell J, Lammerding J. N-terminal tags impair the ability of Lamin A to provide structural support to the nucleus. J Cell Sci. 2024. Published online Aug 2, 2024: jcs.262207.
Keys J, Cheung BCH, Elpers MA, Wu M, Lammerding J. Rear cortex contraction aids in nuclear transit during confined migration by increasing pressure in the cell posterior. J Cell Sci. 2024. 137 (12): jcs260623
Kirby TJ, Zahr HC, Fong EHH, Lammerding J. Eliminating elevated p53 signaling fails to rescue skeletal muscle defects or extend survival in lamin A/C-deficient mice. Cell Death Discovery. 2024. 10(1):245
Odell J, Gräf R, Lammerding J. Heterologous expression of Dictyostelium discoideum NE81 in mouse embryo fibroblasts reveals conserved mechanoprotective roles of lamins. Mol Biol Cell. 2024 Jan 1;35(1):ar7
2023
Odell J, Lammerding J. Lamins as structural nuclear elements through evolution. Curr Opin Cell Biol. 85: 102267
Smolka MB, Lammerding J. ATR takes a crack at the nuclear envelope. 2023. Mol Cell. 83(20): 3588-3590
Elpers MA, Varlet AA, Agrawal R, Lammerding J. Agarose-based 3D cell confinement assay to study nuclear mechanobiology. Current Protocols. 2023. 3(7):e847
Aakula A, Isormursu A, Rupp C, Erickson A, Gupta N, Kauko O, Shah P, Padzik A, Pokharel YR, Kaur A, Li SP, Trotman L, Taimen P, Ranniko A, Lammerding J, Paatero I, Mirtti T, Ivaska J, Westermarck J. PP2A methylesterase PME-1 suppresses anoikis and is associated with therapy relapse of PTEN-deficient prostate cancers. Mol Oncology. 2023. 17(6): 1007-1023
Wallace M, Fedorchak GR, Agrawal R, Gilbert RM, Patel J, Park S, Paszek M, Lammerding J. The Lamin A/C Ig-fold undergoes cell density-dependent changes that altered epitope binding. Nucleus. 2023. 14(1):2180206
2022
Lammerding J, Engler AJ, Kamm R. Mechanobiology of the cell nucleus. APL Bioeng. 2022. 6(4): 040401
Mehl J, Earle A, Lammerding J, Mhlanga M, Vogel V, Jain N. Blockage of Lamin-A/C loss diminishes the pro-inflammatory macrophage response. iScience. 2022. 25(12):105528
Sanketi BD, Zuela-Sopilniak N, Bundschuh E, Gopal S, Hu S, Long J, Lammerding J, Hopyan S, Kurpios NA. Pitx2 patterns an accelerator-brake mechanical feedback through latent TGFβ to rotate the gut. Science. 2022. 377(6613):eabl3921.
Shaw N, Rios-Monterrosa J, Fedorchak G, Ketterer M, Coombs G, Lammerding J, Wallrath L. Effects of mutant lamins on nucleo-cytoskeletal coupling in Drosophila models of LMNA muscular dystrophy. Frontiers Cell Dev Biol. 2022. 10: 934586
Hsia C-R, McAllister J, Hasan O, Judd J, Lee S, Agrawal R, Chang C-Y, Soloway P, Lammerding J. Confined migration induces heterochromatin formation and alters chromatin accessibility. iScience. 2022. 25(9):104978
Bell ES, Shah P, Zuela-Sopilniak N, Kim D, Varlet AA, Morival LP, McGregor AL, Isermann P, Davidson PM, Elacqua JJ, Lakins JN, Vahdat L, Weaver WM, Smolka MB, Span PN, Lammerding J. Oncogene. (2022). Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer. 2022. 41(36): 4211-4230
Zuela-Sopilniak N, Lammerding J. Can’t handle the stress? Mechanobiology and disease. Trends in Molecular Medicine. 2022. 28(9): 710-725
Shah P, McGuigan CW, Cheng S, Vanpouille-Box C, Demaria S, Weiss RS, Lammerding J. ATM modulates nuclear mechanics by regulating lamin A levels. Frontiers Cell Dev Biol. 2022. 10: 875132
Kalukala Y, Stephens AD, Lammerding J, Gabriele S. Mechanics and functional consequences of nuclear deformations. Nature Reviews Mol Cell Biol. 2022.
Agrawal R, Windsor A, Lammerding J. Assembly and use of a microfluidic device to study nuclear mechanobiology during confined migration. Methods Mol Biol. 2022. 2502: 329-349
Tollis S, Rizzotto A, Pham NT, Koivukoski S, Sivakumar A, Shave S, Wildenhain J, Zuleger N, Keys JT, Culley J, Zheng Y, Lammerding J, Carragher NO, Brunton VG, Latonen L, Auer M, Tyers M, Schirmer EC. Chemical interrogation of nuclear size identifies compounds with cancer cell line-specific effects on migration and invasion. ACS Chemical Biology. 2022. 17(3): 680-700
Huth S, Blumber JW, Probst D, Lammerding J, Schwarz US, Selhuber-Unkel C. Quantifying force transmission through fibroblasts: changes of traction forces under external shearing. European Biophysics Journal. 2022. 51(2): 157-169
2021
Wang H, Alarcon CN, Liu B, Watson F, Searles S, Lee CK, Keys J, Pi W, Allen D, Lammerding J, Bui J, Klemke RL. Bioengineering enucleated human cells for in vivo homing and delivery of therapeutic cargos. Nature Biomedical Engineering. Published online Dec 20, 2021
Shah P, Hobson CM, Cheng S, Colville MJ, Paszek MJ, Superfine R, Lammerding, J. Nuclear Deformation Causes DNA Damage by Increasing Replication Stress. Current Biology. 2021. 31(4): 753-765
Siemsen K, Rajput S, Rasch F, Taheri F, Adelung R, Lammerding J, Selhuber-Unkel C. Tunable three-dimensional hydrogel microchannel networks to study confined mammalian cell migration. Advanced Healthcare Materials. 2021. 10(23): e2100625
2020
Lammerding J, Hsia CR. Feeling stressed? Piezo1-mediated loss of heterochromatin buys time for long-term adaptation. Cell. 2020. 181(4):760-762
Earle, A.J., Kirby, T.J., Fedorchak, G.R., Isermann, P., Patel, J., Iruvanti, S., Moore, S.A., Bonne, G., Wallrath, L.L., Lammerding, J. Mutant lamins cause nuclear envelope rupture and DNA damage in skeletal muscle cells. Nature Materials. 2020. 19(4): 464-473
Liu, A., Yu, T., Young, K., Stone, N., Hanasoge S., Kirby, T.J., Varadarajan, V., Colonna, N., Liu, J., Raj, A., Lammerding, J., Alexeev, A., Sulchek, T. Cell Mechanical and Physiological Behavior in the Regime of Rapid Mechanical Compressions that Lead to Cell Volume Change. Small. 2020. 16(2): e1903857.
2019
Mistriotis, P., Wisniewski, E.O., Bera, K., Keys, J., Li, Y., Tuntithavornwat, S., (Et. All) Lammerding, J., Konstantopoulos, K. Confinement hinders motility by inducing RhoA-mediated nuclear influx, volume expansion, and blebbing. Journal of Cell Biology. 2019. 218 (12): pp. 4093-4111.
He, F., Springer, N.L., Whitman, M.A., Pathi, S.P., Lee, Y., Mohanan, S., Marcott, S., Chiou, A.E., Blank, B.S., Iyengar, N., Morris, P.G., Jochelson, M., Hudis, C.A., Shah, P., Kunitake, J.A.M.R., Estroff, L.A., Lammerding, J., Fischbach, C. Hydroxyapatite mineral enhances malignant potential in a tissue-engineered model of ductal carcinoma in situ (DCIS). Biomaterials. 224:Article 119489. 2019
Davidson, P.M., Fedorchak, G.R., Mondésert-Deveraux, S., Bell, E.S., Isermann, P., Aubry, D., Allena, R., Lammerding, J., High-throughput microfluidic micropipette aspiration device to probe time-scale dependent nuclear mechanics in intact cells. Lab on a chip. 2019. 21: 3652-3663.
Zuela-Sopilniak N, Lammerding J. Engineering approaches to studying cancer cell migration in three-dimensional environments. Philosophical Transactions of the Royal Society B: Biological Sciences. 2019. 374(1779).
Krause M, Yang FW, Te Lindert M, Isermann P, Schepens J, Maas RJA, Venkataraman C, Lammerding J, Madzvamuse A, Hendriks W, Te Riet J, Wolf K. Cell migration through three-dimensional confining pores: Speed accelerations by deformation and recoil of the nucleus. Philosophical Transactions of the Royal Society B: Biological Sciences. 2019. 374(1779).
Maurer M, Lammerding J. The Driving Force: Nuclear Mechanotransduction in Cellular Function, Fate, and Disease. Annual Rev of Biomedical Engingeering. 2019. 21: pp. 443-468.
Zhang Q, Tamashunas A, Agrawal A, Torbati M, Katiyar A, Dickinson RB, Lammerding J, Lele TP. Local, transient tensile stress on the nuclear membrane causes membrane rupture. Mol Biol Cell. 2019. 30(7): 899-906.
2018
Kirby, T.J., Lammerding, J. Emerging views of the nucleus as a cellular mechanosensor. Nature Cell Biology. 2018. 20(4), pp. 373-381
Keys J, Windsor A, Lammerding J. Assembly and use of a microfluidic device to study cell migration in confined environments. Methods Mol Biol. 2018. 1840:101-118
Elacqua JJ, McGregor AL, Lammerding J. Automated analysis of cell migration and nuclear envelope rupture in confined environments. PLoS ONE. 2018. 13(4),e0195664
Singh A, Brito I, Lammerding J. Beyond Tissue Stiffness and Bioadhesivity: Advanced Biomaterials to Model Tumor Microenvironments and Drug Resistance. Trends in Cancer. 2018. 4(4), pp. 281-291
Bakhoum SF, Ngo B, Laughney AM, Cavallo JA, Murphy CJ, Ly P, Shah P, Sriram RK, Watkins TBK, Taunk NK, Duran M, Pauli C, Shaw C, Chadalavada K, Rajasekhar VK, Genovese G, Venkatesan S, Birkbak NJ, McGranahan N, Lundquist M, LaPlant Q, Healey JH, Elemento O, Chung CH, Lee NY, Imielenski M, Nanjangud G, Pe’er D, Cleveland DW, Powell SN, Lammerding J, Swanton C, Cantley LC. Chromosomal instability drives metastasis through a cytosolic DNA response. Nature. 2018. 553(7689), pp. 467-472
Yadav SK, Feigelson SW, Roncato F, Antman-Passig M, Shefi O, Lammerding J, Alon R. Elevated nuclear lamin A is permissive for granulocyte transendothelial migration but not for motility through collagen I barriers. Journal of Leukocyte Biology. 2018. 104(2): 239–251
2017
Morelli FF, Verbeek DS, Bertacchini J, Vinet J, Mediani L, Marmiroli S, Cenacchi G, Nasi M, De Biasi S, Brunsting JF, Lammerding J, Pegoraro E, Angelini C, Tupler R, Alberti S, Carra S. Aberrant Compartment Formation by HSPB2 Mislocalizes Lamin A and Compromises Nuclear Integrity and Function. Cell Reports. 2017. 20(9), pp. 2100-2115
Shah P, Wolf K, Lammerding J. Bursting the Bubble – Nuclear Envelope Rupture as a Path to Genomic Instability?. Trends in Cell Biology. 2017. 27(8), pp. 546-555
Mekhdjian AH, Kai F, Rubashkin MG, Prahl LS, Przybyla LM, McGregor AL, Bell ES, Barnes JM, DuFort CC, Ou G, Chang AC, Cassereau L, Tan SJ, Pickup MW, Lakins JN, Ye X, Davidson MW, Lammerding J, Odde DJ, Dunn AR, Weaver VM. Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix. Mol Biol Cell. 2017. 28(11):1467-1488
Etienne-Manneville S, Lammerding J. Connecting the plasma membrane to the nucleus by intermediate filaments. Mol Biol Cell. 2017. 15;28(6):695-696
Isermann P, Lammerding J. Consequences of a tight squeeze: Nuclear envelope rupture and repair. Nucleus. 2017. 8(3):1-7.
Shah P, Wolf K, Lammerding J. Bursting the Bubble – Nuclear Envelope Rupture as a Path to Genomic Instability? Trends Cell Biol. 2017. [Epub ahead of print]
2016
Kirby T, Lammerding J. Cell mechanotransduction: Stretch to express. Nature Materials. 2016(15):1227-9.
Lammerding J, Wolf K. Nuclear envelope rupture: Actin fibers are putting the squeeze on the nucleus. J Cell Biol. 2016 Oct 10;215(1):5.
Cao X, Moeendarbary E, Isermann P, Davidson PM, Wang X, Chen MB, Burkart AK, Lammerding J, Kamm RD, Shenoy VB. A Chemomechanical Model for Nuclear Morphology and Stresses during Cell Transendothelial Migration. Biophysical J. 2016 Oct 4;111(7):1541–52.
Luan JB, Shan HW, Isermann P, Huang JH, Lammerding J, Liu SS, Douglas AE. Cellular and molecular remodelling of a host cell for vertical transmission of bacterial symbionts. Proc Biol Sci. 2016 Jun 29;283(1833).
Bell ES, Lammerding J. Causes and consequences of nuclear envelope alterations in tumour progression. Eur J Cell Biol. 2016 Jun 25. Review.
Fedorchak G, Lammerding J. Cellular and molecular remodelling of a host cell for vertical transmission of bacterial symbionts. Methods Mol Biol. 2016;1411:241-54.
Denais CM, Gilbert RM, Isermann P, McGregor AL, te Lindert M, Weigelin B, Davidson PM, Friedl P, Wolf K, Lammerding J. Nuclear envelope rupture and repair during cancer cell migration. Science. 2016. 352(6283) 353-358.
McGregor AL, Hsia CR, Lammerding J. Squish and squeeze-the nucleus as a physical barrier during migration in confined environments. Curr Opin Cell Biol. 2016. 16(40): 32-40. [Epub ahead of print]
2015
Shav-Tal Y, Lammerding J. Design (and) Principles of Nuclear Dynamics in Stockholm. Nucleus. 2015. 6(6): 425-9.
Davidson PM, Sliz J, Isermann P, Denais C, Lammerding J. Design of a microfluidic device to quantify intra-nuclear deformation during cell migration through confining environments. Integr Biol (Camb). 2015. 30(7): 1534-46.
Mitchell MJ, Denais C, Chan MF, Wang Z, Lammerding J, King MR. Lamin A/C deficiency reduces circulating tumor cell resistance to fluid shear stress. Am J Physiol Cell Physiol. 2015. 309(11): C736-46.
Zwerger M, Roschitzki-Voser H, Zbinden R, Denais C, Herrmann H, Lammerding J, Gruetter MG, and Medalia O. Altering lamina assembly identifies lamina-dependent and -independent functions for A-type lamins. J Cell Sci. 2015. 128(19): 3607-20.
Thomas DG, Yenepalli A, Denais CM, Rape A, Beach JR, Wang Y, Schiemann WP, Baskaran H, Lammerding J, Egelhoff TT. Non-muscle myosin IIB is critical for nuclear translocation during 3-D invasion. J Cell Biol. 2015. 210(4): 583-594.
Dialynas G, Shrestha OK, Ponce JM, Zwerger M, Thiemann DA, Young GH, Moore SA, Yu L, Lammerding J and Wallrath LL. Myopathic lamin mutations cause reductive stress and activate the Nrf2/Keap-1 pathway. PLoS Genetics. 2015. 11(5): e1005231. Published online May 21, 2015.
2014
Davidson P, Denais C, Bakshi M, Lammerding J. Nuclear Deformability Constitutes a Rate-Limiting Step During Cell Migration in 3-D Environments. Cell Mol BioEng J. 2014. Vol 7(3): 293-306
Kaminski A, Fedorchak GR, Lammerding J. The cellular mastermind(?)-mechanotransduction and the nucleus. Prog Mol Biol Transl Sci. 2014;126:157-203.
Fedorchak GR, Kaminski A, Lammerding J. Cellular mechanosensing: Getting to the nucleus of it all. Prog Biophys Mol Biol. 2014 Jul 5. pii: S0079-6107(14)00051-0. doi: 10.1016/j.pbiomolbio.2014.06.009. [Epub]
Davidson PM, Lammerding J. Broken nuclei – lamins, nuclear mechanics, and disease. Trends Cell Biol. 2014 April 24 (4):247-256, Pages 247–256.
Denais C, Lammerding J. Nuclear Mechanics in Cancer. Advances in Experimental Medicine and Biology Cancer Biology, Volume 773; 2014 773:435-70.
2013
Isermann P, Lammerding J. Nuclear mechanics and mechanotransduction in health and disease. Curr Biol. 2013 Dec 16;23(24):R1113-21.
Ho CY, Jaalouk DE, Lammerding J. Novel insights into the disease etiology of laminopathies. Rare Diseases. Published online 2013 Nov 6.
Ho CY, Jaalouk DE, Vartiainen MK, Lammerding J. Lamin A/C and emerin regulate MKL1-SRF activity by modulating actin dynamics. Nature 2013 May; 497(7450):507-11
Zwerger M, Jaalouk D, Lombardi M, Isermann P, Mauermann M, Dialynas G, Herrmann H, Wallrath L, Lammerding J. Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling. Hum. Molecular Genetics 2013 Feb; (12):2335-49;
Rowat AC, Jaalouk DE, Zwerger M, Ung WL, Eydelnant IA, Olins D, Olins A, Herrmann H, Weitz DA, Lammerding J. Nuclear envelope composition determines the ability of neutrophil-type cells to passage through micron-scale constrictions. J. Biol Chem. 2013 Jan; 288(12):8610-8.
2012
Isermann P, Davidson PM, Sliz JD, Lammerding J. Assays to measure nuclear mechanics in interphase cells. Current Protoc Cell Biol. 2012; Chapter 22:Unit 22.16.
Ho CY and Lammerding J. Lamins at a glance. J. Cell Sci. 2012; 125:2087-2093.
2011
Lombardi ML, Zwerger M, Lammerding J. Biophysical assays to probe the mechanical properties of the interphase cell nucleus: substrate strain and microneedle manipulation. JoVE. 2011; 14(55): pii:3087.
Verstraeten VLRM, Peckham LA, Olive M, Capell BC, Collins FS, Nabel EG, Young SG, Fong LG, Lammerding J. Protein farnesylation inhibitors cause donut-shaped cell nuclei attributable to a centrosome separation defect. Proc Natl Acad Sci. 2011; 108(12): 4997-5002.
Lombardi ML, Jaalouk DE, Shanahan CM, Burke B, Roux KJ, Lammerding J. The interaction between nesprins and sun proteins at the nuclear envelope is critical for force transmission between the nucleus and cytoskeleton. J Biol Chem. 2011; 286(30): 26743-53.
Zhao W, Schafer S, Choi J, Yamanaka YJ, Lombardi ML, Bose S, Carlson AL, Phillips JA, Teo W, Droujinine IA, Cui CH, Jan RK, Lammerding J, Love JC, Lin CP, Sarkar D, Karnik R, Karp JM. Cell surface sensors for real-time probing of cellular environments. Nature Nanotechnology. 2011; 6(8): 524-31.
Friedl P, Wolf K, Lammerding J. Nuclear mechanics during cell migration. Curr Opin Cell Biol. 2011; 3(1):55–64
Lombardi ML, Lammerding J. Keeping the LINC: the importance of nucleocytoskeletal coupling in intracellular force transmission and cellular function. Biochem Soc Trans. 2011; 39(6):1729-1734.
Rich JP, Lammerding J, McKinley GH, Doyle PS. Nonlinear microrheology of an aging, yield stress fluid using magnetic tweezers. Soft Matter. 2011; 7: 9933-9943.
Lammerding J. Mechanics of the nucleus. In: Gerthoffer WT, Editor. Handbook of Physiology — Comprehensive Physiology. Wiley-Blackwell. 2011; 1:783-807.
Isermann P, Zwerger M, Lammerding J. Probing the biophysical properties of the cell nucleus and their relevance in health and disease. Cell News, Newsletter of the German Society for Cell Biology (DGZ). 2011; 24–29.
Zwerger M, Ho CY, Lammerding J. Nuclear mechanics in disease. Annu Rev Biomed Eng. 2011; 13:397-428.
2010
Verstraeten VLRM, Lammerding J. Another broken heart: Loss of lamina-associated polypeptide 2-alpha causes systolic dysfunction. Circ Res. 2010; 106(2): 234-237.
Cupesi M, Yoshioka J, Gannon J, Kudinova A, Stewart CL, Lammerding J. Attenuated hypertrophic response to pressure overload in a lamin A/C haploinsufficiency mouse. J Mol Cell Cardiol. 2010; 48(6): 1290-7.
Coffinier C, Jung HJ, Li Z, Nobumori C, Yun UJ, Farber EA, Davies BS, Weinstein MM, Yang SH, Lammerding J, Farahani JN, Bentolila LA, Fong LG, Young SG. Direct synthesis of lamin A, bypassing prelamin A processing, causes mishapen nuclei in fibroblasts but no detectable pathology in mice. J Biol Chem. 2010; 285(27): 20818-26.
Davies B, Barnes R, Tu Y, Ren S, Andrea DA, Spielmann HP, Lammerding J, Wang J, Young SG, Fong LG. An accumulation of nonfarnesylated prelamin A causes cardiomyopathy but not progeria. Hum Mol Gen. 2010; 19(13): 2682-94.
Lombardi ML, Lammerding J. Mechanical properties of the nucleus in disease. In: Shivashankar GV, Editor. Methods in Cell Biology (Vol. 98) — Nuclear Mechanics and Genome Regulation. Amsterdam: Elsevier. 2010; 121-41.
2009
Maloyan A, Osinska H, Lammerding J, Lee RT, Cingolani OH, Kass DA, Lorenz JN, Robbins J.Biochemical and mechanical dysfunction in a mouse model of Desmin-related myopathy. Circ Res.2009; 104: 1021-1028.
Lammerding J, Lee RT. Mechanical properties of interphase nuclei probed by cellular strain application. In: Hancock R, Walker J, editors. The Nucleus (Methods in Molecular Biology). Springer. 2009; Vol. 464:13-26.
Jaalouk DE, Lammerding J. Mechanotransduction gone awry. Nature Rev Mol Cell Biol. 2009; 10(1): 63-73.
Huang H, MacGillivray C, Kwon HS, Lammerding J, Robbins, Lee RT, So PT. Three dimensional cardiac architecture determined by two-photon microtomy. J Biomed Optics. 2009; 14(4): 044029.
Patwari P, Chutkow WA, Cummings K, Verstraeten LRM, Lammerding J, Schreiter ER, Lee RT.Thioredoxin-independent regulation of metabolism by the alpha-arrestin proteins. J Biol Chem. 2009; 284(37): 24996-25003.
2008
Dahl KN, Ribeiro AJS, Lammerding J. Nuclear shape, mechanics, and mechanotransduction. Circ Res. 2008; 102(11): 1307-1318.
Verstraeten VLRM, Lammerding J. Experimental techniques for study of chromatin mechanics in intact nuclei and living cells. Chromosome Res. 2008; vol 30: 226-236.
Verstraeten VLRM, Ji JY, Cummings KS, Lee RT, Lammerding J. Increased mechanosensitivity and nuclear stiffness in Hutchinson-Gilford progeria cells: effects of farnesyltransferase inhibitors. Aging Cell. 2008; 7(3):383-93.
Rowat AC, Lammerding J, Herrmann H, Aebi U. Towards an intergrated understanding of the structure and mechanics of the cell nucleus. BioEssays. 2008; vol 30: 226-236.
2007
Lammerding J, Dahl KN, Discher DE, Kamm RD. Nuclear mechanics and methods. In: Wang YL, Discher DE, editors. Methods in Cell Biology. (Vol 83) — Cell Mechanics. Amsterdam: Elsevier. 2007; 269-294.
Ji JY, Lee RT, Vergnes L, Fong LG, Stewart CL, Reue K, Young SG, Zhang Q, Shanahan CM, Lammerding J. Cell nuclei spin in the absence of lamin B1. J Biol Chem. 2007; 282(27): 20015-20026.
Lammerding J, Lee RT. Torn apart–Membrane rupture in muscular dystrophies and associated cardiomyopathies. Invited commentary. J Clin Invest. 2007; 177(7): 1749-52.
2006
Rowat AC, Lammerding J, Ipsen JH. Mechanical properties of the cell nucleus and the effect of emerin deficiency. Biophys J. 2006; 91(12): 4649-4664.
Lammerding J, Fong LG, Ji JY, Reue K, Stewart CL, Young SG, Lee RT. Lamin A and lamin C but not lamin B regulate nuclear mechanics. J Biol Chem. 2006; 281(35): 25768-25780.
Fong L, Ng JK, Lammerding J, Vickers TA, Meta M, Cote N, Gavino B, Qiao X, Chang SY, Young SR, Yang SH, Stewart CL, Lee RT, Bennet CF, Bergo MO, Young SG. Prelamin A and lamin A appear to be dispensable–implications for progeria. J Clin Invest. 2006; 116(3): 743-752.
2005
Hakuno D, Takahashi T, Lammerding J, Lee RT. Focal adhesion kinase signaling regulated cardiogenesis of embryonic stem cells. J Biol Chem. 2005; 280(47): 39534-39544.
Lammerding J, Hsiao J, Schulze PC, Kozlov S, Stewart CL, Lee RT. Abnormal nuclear shape and impaired mechanotransduction in emerin-deficient cells. J Cell Biol. 2005; 170(5): 781-791.
Lammerding J, Lee RT. The nuclear membrane and mechanotransduction: impaired nuclear mechanics and mechanotransduction in lamin A/C deficient cells. In: Novartis Found Symp. 2005; 264:264–73; discussion 273–8.
2004
Lammerding J, Schulze PC, Takahashi T, Kozlov S, Sullivan T, Kamm RD, Stewart CL, Lee RT. Lamin A/C deficiency causes defective nuclear mechanics ad mechanotransduction. J Clin Invest. 2004 Feb; 113(3): 370-378.
Lammerding J, Kamm, RD, Lee RT. Mechanotransduction in cardiac myocytes. Ann N Y Acad. Sci. 2004; 1015:53–70.
2003
Lammerding J, Huang H, So PT, Kamm RD, Lee RT. Quantitative measurements of active and passive mechanical properties of adult cardiac mycytes. IEEE Eng Med Biol Mag. 2003 Sep/Oct; 22(5): 124-127.
Karcher H, Lammerding J, Huang H, Lee RT, Kamm RD, Kaazempur-Mofrad MR. A three-dimensional viscoelastic model for cell deformation with experimental verification. Biophys J. 2003 Nov; 85(5): 3336-3349.
Lammerding J, Kazarov AR, Huang H, Lee RT, Hemler ME. Tetraspanin CD151 regulates alpha6beta1 integrin adhesion strengthening. Proc Natl Acad Sci. 2003 Jun; 100(13): 7616-7621.
2002
Lammerding J, Huang H, So PT, Kamm RD, Lee RT. Quantitative measurements of active and passive mechanical properties of adult cardiac myocytes. Conference Proceedings. Second Joint IEEE EMBS/BMES Conference 2002. 24th Annual Conference of the Engineering in Medicine and Biology Society. Annual Meeting of the Biomedical Engineering Society. 2002; p5. 1, p. 298-9, vol 1.
Lee, R.T., Lammerding, J. Signaling pathways that influence extracellular remodeling. J Card Fail. 2002; 8(6 Suppl):S339–43.
1999
Pandorf T, Haddi A, Wirtz DC, Lammerding J, Forst R, Wechert D. Numerical simulation of adaptive bone remodeling. J Theor Appl Mech. 1999; 37(3): 639-658.
